Thank you for the great question, Cynthia!
In this instance, per RUEB 7.5.2, the second option you provide would be the best way to present the equation. Inserting a grade 1 symbol indicator before the question mark helps to reinforce its role as a question mark and dismisses any ambiguity regarding the symbol.
I would also like to point out that RUEB 7.5.4 is a bit more specific to this situation; in particular, the first sentence which reads:
RUEB 7.5.4 Place a grade 1 symbol indicator before a question mark which follows a space, hyphen or dash.
In the provided equation, the question mark follows a space and would therefore need the grade 1 symbol indicator before it.
;;;5#ae9#cc,p
\o ;8″65<“-#a>9#j;e”65#j9#jv;’
