You always come up with the best questions!
I would do a couple of things to aid the reader - I would use bar lines in the RH to show the division of the smaller measures. Then I would use the coincidence signs at the start of the second RH measure and the middle of the LH measure, where the notes align rhythmically.
Does the print music have the measures numbered? If so, follow print for the measure numbering. If not, I'd probably follow the large measure divisions for numbering, of course with a TN indicating said decisions.
I've attached a doc showing how I might braille it. (Can't figure out how to get it into this text box...)
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