If there is a number associated with the degree sign, followed by the letter F or C, the degree sign is assumed to be related to the number and the abbreviation is spaced away from the number and degree sign and preceded by the letter indicator. The abbreviation is punctuated in literary mode.
If there is no number involved, the degree sign pertains to the letter F or C -- it is a left superscript to a letter, there is no space between the degree sign and the letter and a baseline indicator returns the level to the baseline. No letter indicator is used on the letter F or C. This math expression is punctuated mathematically.
19,872,369°C [braille]#19,872,369~.* ;,c