Thank you for the question, Kimberly!
The single-cell Nemeth Code bold indicator for the 6 does not carry through the sign of operation. You do not need a numeric indicator before the 4.
Rule V, Section 32.d of the Nemeth Code says in part, "When a type-form indicator is used with numerals only, it is effective until terminated by a space, a numeric indicator, or any non-numeric symbol." The operation symbol is a non-numeric symbol.
Braille on!
–Kyle